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TRAF6 polyclonal antibody
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TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways. Western blot analysis of L5178Y (1), WR19L (2) and NIH/3T3 (3) cells, probed with TRAF6 pAb. Western blot analysis of L5178Y (1), WR19L (2) and NIH/3T3 (3) cells, probed with TRAF6 pAb.
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| Alternative Name TNF receptor-associated factor 6 | Application IP, WB | Application Notes Detects a band of ~58kDa by Western blot.143090-92-0 In Vivo | Formulation Liquid.503468-95-9 In Vitro In PBS containing 50% glycerol.PMID:30725819 | Host Rabbit | Immunogen Recombinant mouse TRAF6 (N-terminal fragment). | Recommendation Dilutions/Conditions Immunoprecipitation (2-4µL/100-500 µl cell extract from 5×106 cells)Western Blot (1:1000, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. | Species Reactivity Mouse | UniProt ID P70196 | Unit of Measure (UM) µl
