Biotinylated Human 4-1BB Ligand/TNFSF9 Trimer Protein, hFc Tag

Description :
FAQ COA 已发表文献 4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane protein domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant Human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues. 产品性质 Synonyms 41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9 Uniprot No. P41273 Source Recombinant Biotinylated Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from HEK293 Cells with monomeric hFc tag at the N-terminal. It contains Arg71-Glu254. Molecular Weight The protein has a predicted MW of 84.3 kDa same as Tris-Bis PAGE result. Physical Appearance Liquid Solution Purity > 95% as determined by SDS-PAGE and HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Supplied as 0.22m filtered solution in PBS (pH 7.4).