Recombinant Mouse VEGFR2/KDR Protein, His Tag

Description :
FAQ COA 已发表文献 VEGFR2 (KDR/Flk-1), VEGFR1 (Flt-1) and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. 产品性质 Synonyms CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73 Uniprot No. P35918-1 Source Recombinant Mouse VEGF R2/KDR Protein is expressed from HEK293 Cellswith His tag at the C-terminal. It contains Ala20-Glu762. Molecular Weight The protein has a predicted MW of 84.11 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 g/ml is recommended. Dissolve the lyophilized protein in distilled water.