Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein, His-Avi Tag

Description :
FAQ COA 已发表文献 Guanylyl Cyclase C (GUCY2C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (GC) family expressed by intestinal epithelial cells from the duodenum to rectum. The ECD of mouse GUCY2C shares 70% and 88% amino acid sequence identity with the ECD of human and rat GUCY2C, respectively. Endogenous ligands of GUCY2C include guanylin and uroguanylin. GUCY2C is also expressed in the brain and is implicated in attention deficiency and hyperactive behavior. 产品性质 Synonyms Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL Uniprot No. Q3UWA6-1 Source Recombinant Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Val20-Met433. Molecular Weight The protein has a predicted MW of 50.01 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result. Physical Appearance Liquid Solution Purity > 95% as determined by SDS-PAGE and HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Supplied as 0.22m filtered solution in PBS (pH 7.4).