Biotinylated Human Siglec-3/CD33 Protein, His-Avi Tag

Description :
FAQ COA 已发表文献 Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. 产品性质 Synonyms CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67 Uniprot No. P20138-1 Source Recombinant Biotinylated Human Siglec-3/CD33 Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Asp18-His259. Molecular Weight The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result. Physical Appearance Liquid Solution Purity > 95% as determined by SDS-PAGEand > 90% as determined by HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Supplied as 0.22m filtered solution in 20mM PB, 500mM NaCl (pH 8.0).