Recombinant Rhesus TARC/CCL17

Description :
FAQ COA 已发表文献 TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Rhesus MacaqueTARC is an 8.1 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Product Properties Synonyms Thymus and Activation Regulated Chemokine, CCL17, ABCD-2 Accession Q8HYP9 GeneID 574180 Source E.coli-derived Rhesus Macaque TARCprotein,Ala24-Ser94. Molecular Weight Approximately8.1 kDa. AA Sequence ARGTNVGREC CLKYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQNKAIC SDPNDKKVKK ALKYLQSLER S Tag None Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 97% by SDS-PAGE and HPLC analyses. Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/mL. Endotoxin Formulation Lyophilized from a 0.2 m filtered concentrated solution in 20 mM PB, 300 mM NaCl, pH 7.4, with 0.02 % Tween-20. Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20C. Further dilutions should be made in appropriate buffered solutions.