87 0.00938 0.00152 0.00776 0.00996 0.0044 0.00321 0.00133 0.00687 0.00357 0.00242 0.00775 0.00352 0.00841 0.00974 0.00009 0.00003 0.00232 0.00232 ** *** * * ** * * * * * *solute carrier family members 25 (mitochondrial carrier phosphate carrier) member 25 ptc7 protein phosphatase homolog (cerevisiae) ptc7 protein phosphatase homolog (cerevisiae)tbt-binding protein tbt-binding protein solute carrier household memberglycerol-3-phosphate dehydrogenase glycerol-3-phosphate dehydrogenase novel protein vertebrate stabilinvacuolar protein sorting 4b kiaa1219 proteintuberous sclerosis 1 dipeptidyl peptidase 7 dipeptidyl peptidase 7 loc795887 protein loc795887 protein novel protein novel proteinRobinson et al. BMC Genomics 2014, 15:541 http://www.biomedcentral/1471-2164/15/Page 7 ofTable 4 Suggestive and considerable QTL for trait hours of survival immediately after challenge using a. hydrophila detected applying PLINK (QFAM) and GenAbel (FASTA and GRAMMA) analyses in 21 L. rohita households (Continued)23 24 24 25 27.four 55.9 55.9 46.1 64731_210 67606_298 67606_298 54056_576 QFAM FASTA GRAMMA FASTA 1022 979 979 979 -3.63(1.14) -2.07 (0.83) 1.7(0.65) 1.41 ten.21 6.25 6.87 0.00308 0.0014 0.00101 0.00876 * * serine long chain base subunit 1 serine lengthy chain base subunit 1 n-ethylmaleimide sensitive fusion protein attachment protein alphaLG, linkage group; Pos, location on LG in centimorgans; N, variety of progeny and parents analysed; Impact, allele substitution effect with the minor allele with normal error in parenthesis (FASTA and GRAMMAS); Stat, test statistic linear regression coefficient for QFAM, chi-square with one degree of freedom for FASTA and GRAMMA analyses; P, point-wise empirical P-value (QFAM) or permuted P-value with a single degree of freedom corrected for inflation aspect lambda (FASTA and GRAMMA); Sig, significance immediately after Bonferroni correction (*, P 0.β-Tocotrienol MedChemExpress 05; **, P 0.Catumaxomab Immunology/Inflammation 01; ***, P 0.001). GeneID, closest SNP homology from BLAST. Tests have been viewed as suggestive when P 0.01 before Bonferroni correction.has suggestive associations with both traits (Tables four, 5 and 6). SNP 16321_60 with homology for the integrin alpha fg-gap repeat maps to 48 cM on LG2, inside 1 cM of three SNPs with suggestive associations on hours of survival (Further file 1, Table four).PMID:32926338 SNP 134389_297 with homology to lymphocyte-specific protein tyrosine kinase maps roughly 2 cM from SNP 89585_200 (suggestive association with dead or alive) on LG3 (More file 1, Tables 5 and 6). SNP 98520_125 with homology to proteasome subunit beta type-6 precursor maps to the identical position, 9.6 cM along LG5, as SNP 4797_109 (suggestive association with hours of survival) (Further file 1, Tables 4 and six). SNPs 111876_59 and 53025_556 with homology to the main histocompatibility locus I antigen (MHC I) and also the c-type lectin receptor c map to 13 cM and 18 cM on LG5 respectively 3.4 and five.8 cM from SNPs 4797_109 (suggestive association to hours of survival for the GRAMMA and FASTA tests, Extra file 1, Tables four and 6) and 83820_94 (suggestive association with both hours survival and dead or alive) respectively (More file 1, Tables 4, 5 and 6). A SNP with homology to e3 ubiquitin ligase (110314_603) happens at the same place as SNP 62374_157 (significant association with hours of survival, FASTA P 0.05 and GRAMMA P 0.01), while another SNP with homology to immunity related gtpase e4 (134666_118) maps towards the exact same position as SNP 87974_385 (sec14-like 1, suggestive associations with hours of surviv.
