D also be able to remineralize the structural damage surface. In the same time, the microspheres could also be capable of remineralize the brought on by the bleaching. structural damage brought on by the bleaching.Figure Left: (A,B) Scanning electron SN-38 Autophagy microscopy (SEM) micrographs and (C) powder X-ray Figure 6.6. Left: (A, B) Scanning electron microscopy (SEM) micrographs and (C) powder X-ray diffraction (PXRD) patterns TCP microspheres. Suitable: ex vivo bleaching effect of of microspheres diffraction (PXRD) patterns of of TCP microspheres. Appropriate: ex vivo bleaching effectthe the microspheres containing hydrogen peroxide and carbamide peroxide. (Reprinted from [109].) containing hydrogen peroxide and carbamide peroxide. (Reprinted from [109]).CaPs have also discovered prosperous application as an adjuvant prevalent bleaching CaPs have also found profitable application as an adjuvant ofof common bleaching agents [12024]. this case, CaPs have an indirect action, as Biotin-azide Chemical because the whitening is generated agents [12024]. InIn this case, CaPs have an indirect action,the whitening is generated by by the bleaching components and the of CaPs of CaPs is always to remineralize broken the bleaching ingredients plus the purposepurpose is to remineralize the enamel the enamel damaged by the bleaching. The majority of functions this application of CaP components by the bleaching. The majority of performs reporting on reporting on this application of CaP components employ casein-phosphopeptide-stabilized ACP (CPP-ACP) [12022,124], employ casein-phosphopeptide-stabilized ACP (CPP-ACP) [12022,124], as this material isas this material is currently commercially available and was proved to have a [59], already commercially offered and was proved to possess a sturdy remineralizing actionstrong remineralizing action [59], despite the fact that in [123]. despite the fact that in 1 study HA was also usedone study HA was also employed [123]. Lastly, all the articles on this topic proved that the presence CaPs did not hinder Ultimately, each of the articles on this subject proved that the presence ofof CaPs didn’t hinder the whitening action from the bleaching agents but allowed such agents overcome their the whitening action from the bleaching agents but allowed such agents toto overcome their drawbacks. Certainly, the mixture of CaPs with bleaching agents improved tooth drawbacks. Certainly, the mixture of CaPs with bleaching agents improved tooth whiteness plus the very same time prevented enamel demineralization, hardness loss, tooth whiteness and atat the exact same time prevented enamel demineralization, hardness loss, tooth sensitization, and surface roughening [12024]. sensitization, and surface roughening [12024]. The outstanding whitening effect of CaPs reported in scientific literature isis reflected by The fantastic whitening effect of CaPs reported in scientific literature reflected by the high quantity of patents comprising CaPs as abrasive and bleaching agents reported in bleaching agents reported the high quantity of patents comprising CaPs as in Table1. In general, about half on the patents protect toothpaste or gel formulation Table 1. Generally, about half the patents guard toothpaste or gel formulation containing CaPs [12531], when the other half protect CaPs as an ingredient for generic containing CaPs [12531], when the other half shield CaPs as an ingredient for generic whitening solutions [13247]. This indicates that there is is an interest in the use of CaP both whitening merchandise [13247]. This indicates that there an interest.