Recombinant Human uPAR/PLAUR Protein, His-Avi Tag

Description :
FAQ COA 已发表文献 The urokinase-type Plasminogen Activator (uPA) is one of two activators that converts the extracellular zymogen plasminogen to plasmin, a serine protease that is involved in a variety of normal and pathological processes that require cell migration and/or tissue destruction.Both the scuPA and tcuPA bind with high-affinity to the cell surface via the glycosyl phosphatidylinositol-linked receptor uPAR which serves to localize the uPA proteolytic activity. 产品性质 Synonyms U-PAR; uPAR; CD87; PLAUR; MO3; UPAR Uniprot No. Q03405-1 Source Recombinant Human uPAR/PLAUR Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Leu23-Gly305. Molecular Weight The protein has a predicted MW of 34.36 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 g/mL is recommended . Dissolve the lyophilized protein in distilled water.