Biotinylated Human IL-1R3/IL-1 RAcP Protein, His-Avi Tag

Description :
FAQ COA 已发表文献 IL-1R3, also known as IL-1 Receptor Accessory Protein (IL-1 RAcP), is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins.It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36.Within the ECD, human IL-1 RAcP shares 86% aa sequence identity with mouse and rat IL-1 RAcP.It is a subunit of the functional signaling complex with IL-1 RI and associates with IL-1 RII in a non-signaling receptor complex. In addition, it interacts with ST2/IL-1 R4 on mast cells and Th2 cells to create a functional IL-33 receptor complex. 产品性质 Synonyms IL1RAP; IL-1RAP; C3orf13; IL-1 R3; IL-1 RAcP Uniprot No. Q9NPH3-1 Source Recombinant Biotinylated Human IL-1R3/IL-1 RAcP Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Ser21-Glu359. Molecular Weight The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result. Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 95% as determined by SDS-PAGE and HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100g/mLis recommended. Dissolve the lyophilized protein in distilled water.