Biotinylated Human Her4/ErbB4 Protein, His-Avi Tag

Description :
FAQ COA 已发表文献 Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. 产品性质 Synonyms p180erbB4; 4ICD; E4ICD; HER4; ErbB4; MGC138404; ALS19 Uniprot No. Q15303-1 Source Recombinant Biotinylated Human Her4/ErbB4 Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Gln26-Pro651. Molecular Weight The protein has a predicted MW of 72.7 kDa. Due to glycosylation, the protein migrates to 75-110 kDa based on Tris-Bis PAGE result. Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 95% as determined by SDS-PAGEand HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100g/mLis recommended. Dissolve the lyophilized protein in distilled water.