Product Name :
Biotinylated Human B7-H3 (4Ig)/B7-H3b Protein, His-Avi Tag
Description :
FAQ COA 已发表文献 Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Its precursor contains a 26 aa signal sequence, a 435 aa extracellular region, a 31 aa transmembrane domain, and a 42 aa cytoplasmic tail. The four Ig-like domains alternate between V_x005f_x001e_type and C_x005f_x001e_type, and apparently are the consequence of a V_x005f_x001e_C type tandem duplication. Human B7-H3b binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine release. 产品性质 Synonyms B7-H3; CD276; PSEC0249;4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276 Uniprot No. Q5ZPR3-1 Source Recombinant Biotinylated Human B7-H3 (4Ig)/B7-H3b Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Gly27-Thr461. Molecular Weight The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 95% as determined by SDS-PAGE and HPLC Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100g/mLis recommended. Dissolve the lyophilized protein in distilled water.
Storage :
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