Recombinant Human BCMA Protein,His-Avi Tag

Description :
FAQ COA 已发表文献 BCMA, B cell maturation antigen, is a member of the TNF receptor superfamily.(TNFRSF17). BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines.The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. 产品性质 Synonyms CD269; TNFRSF17; BCMA; BCM; TNFRSF13A Uniprot No. Q02223 Source Recombinant Human BCMA/TNFRSF17 Trimer Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Met1-Ala54. Molecular Weight The protein has a predicted MW of 29.5 kDa. Due to glycosylation, the protein migrates to 30-48 kDa based on Tris-Bis PAGE result. Purity > 95% as determined by Tris-Bis PAGE and HPLC. Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than100 g/ml`is recommended. Dissolve the lyophilized protein in distilled water.