Recombinant Human SLAMF7/CRACC/CD319(hFc Tag)

Description :
FAQ COA 已发表文献 CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, SLAMF7, and CD319, is a 65-75 kDa typeI transmembrane glycoprotein intheSLAM subgroup of the CD2 family. Within the ECD, human CRACC shares 54%and 52%aa sequence identity with mouse and rat CRACC, respectively. There are seven known isoforms of CRACC which are distinguished by deletions and/or substitutions in both their ECD and cytoplasmic domains. CRACC is expressed on the surface of NK cells, CD8+Tcells, activated Bcells, and mature dendritic cells. 产品性质 别名Synonyms CD2 subset 1, CRACC, CD319, CS1, Novel Ly9, SLAMF7, 19A, FOAP-12 Uniprot No. Q9NQ25-1 Source HEK293 Cells-derivedHuman SLAMF7/CRACC/CD319Protein, Ser23-Met226with hFc tagat the C-terminal 分子量(Molecular Weight) Approximately 49.2kDa.Due to glycosylation, the protein migrates to 68-80kDa based on Tris-Bis PAGE result. 外观(Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 95% as determined by SDS-PAGEand HPLC Activity ELISAData: Immobilized Human SLAMF7, hFc Tag at 0.5g/mL(100L/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC507.3ng/mLdetermined by ELISA. 内毒素Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from 0.22m filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. 复溶Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 g/mL`is recommended (usually we use 1mg/mLsolution for lyophilization). Dissolve the lyophilized protein in distilled water.