Recombinant Mouse RANTES/CCL5

Description :
FAQ COA 已发表文献 RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant MouseRANTES is a 7.9kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Product Properties Synonyms MuRantes, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES Accession P97545 GeneID 29397 Source E.coli-derived Mouse RANTESprotein,Ser24–Ser91. Molecular Weight Approximately 7.9 kDa. AA Sequence SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS Tag None Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 97% by SDS-PAGE and HPLC analyses. Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T lymphocytes is in a concentration range of 1.0-10 ng/mL. Endotoxin Formulation Lyophilized from a 0.2 m filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA. Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20C. Further dilutions should be made in appropriate buffered solutions.