Recombinant Mouse MIG/CXCL9 Protein

Description :
FAQ COA 已发表文献 CXCL9 is a member of the CXC family and has an important role in the chemotaxis of immune cells. The mouse CXCL9 shares 75% and 88% a.a. sequence identity with human and rat CXCL9. It is a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response and chemotactic for activated T-cells. Product Properties Synonyms C-X-C motif chemokine 9, CXCL9, Gamma-interferon-induced Monokine, Humig, MIG, Small-inducible Cytokine B9 Accession P18340 GeneID 17329 Source E.coli-derived mouse MIG/CXCL9 protein, Thr22-Thr126 (S72N) . Molecular Weight Approximately 12.2kDa. AA Sequence TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT Tag None Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity >95% by SDS-PAGE and HPLC analyses. Biological Activity The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 0.1-1.0 ng/mL.Fully biologically active when compared to standard. Endotoxin 1.0EU per 1g of the protein by the LAL method. Formulation Lyophilized from a 0.2 m filtered concentrated solution in2 PBS, pH 7.4. Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.