Recombinant Human GDF-15 Protein

Description :
Synonyms Growth Differentiation Factor 15,MIC-1 Uniprot No. Q99988 Source Human GDF-15 Proteinis expressed from E. coli.It contains Ala197-Ile308 Molecular Weight Predicted molecular mass of approximately 12 kDa in SDS-PAGE under reducing condition. Biological Activity Measured by its binding ability in a functional ELISA. When rHuGDF-15/MIC-1 is used at 0.5 g/mL, the concentration of Recombinant Human Activin RIB/ALK-4 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-3 g/mL. Purity > 95% as determined by SDS-PAGE. Endotoxin Formulation Lyophilized from 0.2 m filtered concentrated solution in 4 mM HCl. Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.5 mg/mL. Further dilutions should be made in appropriately buffered solutions.