Recombinant Human Apolipoprotein A-I Protein

Description :
FAQ COA 已发表文献 ApolipoproteinA1 (ApoA1) is a 28kDa glycoprotein that is the major protein component of high density lipoprotein (HDL) particles. HDL particles play a central role in the reverse transport of cholesterol from peripheral tissues to the liver. HDL is known as goodcholesterol due to its ability to facilitate the removal of cholesterol from macrophage foam cells in atherosclerotic plaques and thereby retard the progression of disease. ApoA1 is secreted from hepatocytes with variable amounts of lipidation. Product Properties Synonyms Alp-1Brp-14; Ltw-1 Accession P02647 GeneID 335 Source Recombinant Human ApoA-I Proteinis expressed from Yeast Cells with His tag at the C-terminal. It contains Asp25-Gln267 Molecular Weight Approximately 28.9kDa. AA Sequence DEPPQSPWDR VKDLATVYVD VLKDSGRDYV SQFEGSALGK QLNLKLLDNW DSVTSTFSKL REQLGPVTQE FWDNLEKETE GLRQEMSKDL EEVKAKVQPY LDDFQKKWQE EMELYRQKVE PLRAELQEGA RQKLHELQEK LSPLGEEMRD RARAHVDALR THLAPYSDEL RQRLAARLEA LKENGGARLA EYHAKATEHL STLSEKAKPA LEDLRQGLLP VLESFKVSFL SALEEYTKKL NTQ Purity > 95% by SDS-PAGE. Endotoxin .0EU per 1g of the protein by the LAL method. Formulation The0.2 m filtered concentrated solution in PBS, pH 7.4.