Arch work was to check the presence or absence on the phytochemical constituents within the selected medicinal plants and also to verify their antimicrobial effect. Supplies and strategies: This present study involves phytochemical evaluation from aqueous leaf extract of medicinal plants of taxonomical identification Rubus ellipticus, which have been collected from Dhankuta area of Nepal for the phytochemical screening. Benefits: The different test was performed for the qualitative tests of leaf extract along with the methanol extract was checked for antimicrobial impact against 4 bacterial strains: Pseudomonas aerogens, Staphylococcus aureus, E. coli, and K. Pneumonia. Rubus GW768505A supplier ellipticus contain all of the phytochemicals (Flavonoid, alkaloid, tannin, saponin, terpenoid) and it showed sensitivity towards grampositive bacteria i.e. S. aureus and Pseudomonas aerogens and resistance to E. coli and K. pneumonia. Conclusions: It truly is anticipated that the vital phytochemical recognized in our medicinal plant are going to be valuable in curing various illnesses and led a base to study on R. ellipticus leaves in food and pharmaceutical application.Fig. 1 Structures of microcosamines D (1) and E (2)Chin Med 2018, 13(Suppl 1):Web page 38 of80 Impact of ultrafine grinding on physicochemical and antioxidant properties of dietary fiber from wine grape pomace Fengmei Zhu1, Bin Du2, Jun Li1 1 College of Food Science and Technologies, Hebei Standard University of Science and Technology, Qinhuangdao 066600, China; 2Analysis and Testing Center, Hebei Regular University of Science and Technologies, Qinhuangdao 066600, China Correspondence: Jun Li Journal of Chinese Medicine 2018, 13(Suppl 1):80 Background: Dietary fiber (DF), defined as “edible components of plants or Chloramphenicol palmitate Epigenetics analogous carbohydrate which might be resistant to digestion and absorption within the human small intestine with total or partial fermentation within the significant intestine” [1], is abundant in plant merchandise which include fruits, vegetables, and grains. DF has attracted escalating interests in current years as numerous research have revealed that it could possibly be involved in illness preventive and health promotive activities, including attenuation of blood cholesterol and glucose, laxative impact and reduction of risk of colon cancer, heart disease and obesity [2, 3]. Materials and techniques: Wine grape pomace dietary fiber (DF) powders was prepared by superfine grinding, whose effects have been investigated on the composition, functional and antioxidant properties in the wine grape pomace DF goods. The antioxidant activities of wine grape pomace and DF prior to and just after grinding have been when it comes to 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, 2,2-azinobis(3-ethylbenzothiozoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP) and total phenolic content material (TPC). Final results: The results showed that superfine grinding could effectively pulverize the fiber particles to submicron scale. As particle size decrease, the functional properties (water holding capacity, water retention capacity, swelling capacity, oil binding capacity and nitrite ion absorption capacity) of wine grape pomace DF were significantly (p 0.05) decreased along with a redistribution of fiber elements from insoluble to soluble fractions was observed. Conclusions: Compared with DF ahead of and after grinding, micronized insoluble DF showed improved ABTS radical scavenging activity, ferric minimizing antioxidant energy and TPC yet decreased DPP.