Arch function was to verify the presence or absence of the phytochemical constituents in the selected medicinal plants and also to verify their antimicrobial effect. Components and methods: This present study involves phytochemical evaluation from aqueous leaf extract of medicinal plants of taxonomical identification Rubus ellipticus, which had been collected from Dhankuta region of Nepal for the phytochemical screening. Benefits: The distinct test was performed for the qualitative tests of leaf extract as well as the methanol extract was checked for antimicrobial impact against 4 bacterial strains: Pseudomonas aerogens, Staphylococcus aureus, E. coli, and K. Pneumonia. Rubus ellipticus contain all of the phytochemicals (Flavonoid, alkaloid, tannin, saponin, terpenoid) and it showed sensitivity towards grampositive bacteria i.e. S. aureus and Pseudomonas aerogens and resistance to E. coli and K. pneumonia. Conclusions: It is expected that the critical phytochemical recognized in our medicinal plant might be valuable in curing diverse ailments and led a base to study on R. ellipticus leaves in food and pharmaceutical application.Fig. 1 Structures of microcosamines D (1) and E (two)Chin Med 2018, 13(Suppl 1):Page 38 of80 Impact of ultrafine grinding on physicochemical and antioxidant properties of dietary fiber from wine grape pomace Fengmei Zhu1, Bin Du2, Jun Li1 1 College of Food Science and Technologies, Hebei Regular University of Science and Technologies, Qinhuangdao 066600, China; 2Analysis and Testing Center, Hebei Regular University of Science and Technologies, Qinhuangdao 066600, China Correspondence: Jun Li Journal of Chinese Medicine 2018, 13(Suppl 1):80 Background: Dietary fiber (DF), defined as “edible components of plants or analogous carbohydrate which might be resistant to digestion and absorption inside the human smaller intestine with complete or partial fermentation within the massive intestine” [1], is abundant in plant merchandise for instance fruits, vegetables, and grains. DF has attracted increasing interests in recent years as several research have revealed that it could possibly be involved in illness preventive and wellness promotive activities, including attenuation of blood cholesterol and glucose, laxative effect and reduction of risk of colon cancer, heart illness and obesity [2, 3]. Supplies and approaches: Wine grape pomace dietary fiber (DF) powders was ready by superfine grinding, whose effects had been investigated on the composition, functional and antioxidant properties in the wine grape pomace DF merchandise. The antioxidant activities of wine grape pomace and DF ahead of and right after grinding had been with regards to 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical Diflucortolone valerate Purity scavenging activity, two,2-azinobis(3-ethylbenzothiozoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity, ferric lowering antioxidant power (FRAP) and total phenolic content material (TPC). Outcomes: The results showed that superfine grinding could effectively pulverize the fiber particles to submicron scale. As particle size lower, the functional properties (water holding capacity, water retention capacity, swelling capacity, oil binding capacity and nitrite ion absorption capacity) of wine grape pomace DF had been drastically (p 0.05) decreased plus a redistribution of fiber components from insoluble to soluble fractions was CP-465022 Technical Information observed. Conclusions: Compared with DF just before and just after grinding, micronized insoluble DF showed improved ABTS radical scavenging activity, ferric lowering antioxidant power and TPC however decreased DPP.